TUDCA Acid is an orally bioavailable and effective inhibitor of apoptosis by exhibiting antioxidant properties, maintaining mitochondrial membrane potential, and preventing cytochrome c release.
Tauroursodeoxycholic acid, more commonly referred to as TUDCA, is a bile salt that is found naturally occurring in the body. When regular bile salts reach the intestines, they can be metabolized by bacteria into UDCA and then later bound to a taurine molecule to become TUDCA. TUDCA is able to reduce stress to any cell’s Endoplasmic Reticulum; an organelle in cells that serves as a highway from the nucleus out into the cytoplasm, and aids in folding proteins. Through reducing ER stress, TUDCA has been implicated in a wide range of beneficial metabolic effects such as reducing insulin resistance and diabetes, being a neurological protection agent and has been used for conditions called liver cholestasis.
Out of stock
What is TUDCA Acid?
Tauroursodeoxycholic acid (TUDCA) is an ambiphilic bile acid. It is the taurine conjugate form of ursodeoxycholic acid (UDCA). TUDCA prevents apoptosis (programmed cell death) with its role in the BAX pathway. BAX, a molecule that is translocated to the mitochondria to release cytochrome C, initiates the cellular pathway of apoptosis.TUDCA prevents BAX from being transported to the mitochondria. This protects the mitochondria from perturbation and the activation of caspases.
TUDCA Acid Benefits and Uses
Studies have shown that TUDCA Acid may have the following benefits:
- Protects brain from degeneration
- Anti-inflammatory effects
- Improves systemic insulin resistance
- Hepatic protection
Additional Information on TUDCA Acid
TUDCA has been used in Chinese traditional medicine for centuries to treat a range of ailments. In Chinese medicine, it was originally harvested from the bile of bears. Bear bile is made up of more than 50% TUDCA. Some scientists believed this is what gives bears the ability to hibernate for extended periods of time. TUDCA is a potent inhibitor of apoptosis, in part by interfering with the upstream mitochondrial pathway of cell death, inhibiting oxygen-radical production, reducing endoplasmic reticulum (ER) stress, and stabilizing the unfolded protein response (UPR). TUDCA plays an important role in protecting against cell death in certain retinal disorders, such as retinitis pigmentosa. It has been shown to reduce ER stress associated with elevated glucose levels in diabetes by inhibiting caspase activation, up-regulating the UPR, and inhibiting reactive oxygen species.
Where to Buy TUDCA Acid?
Botany offers high-quality TUDCA Acid powder in a quantity of 10g. Our TUDCA Acid has been lab-tested and verified for both product purity and identity.
For Best Results:
- Take 500 milligrams orally once a day.
- Sensitive to flavors? Feel free to mix your powder into your favorite food or drink.
- Store in a cool, dry place away from light.
- A 10 grams jar contains 20x 500mg servings.
- We recommend using a milligram scale to accurately measure dosages.
One Serving (500mg) Contains:
- TUDCA Acid 500mg
- Other Ingredients: None
- No artificial colors, preservatives, or additives.
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
Consult your physician if pregnant, nursing, have or suspect a medical condition.
Do not use if tamper seal is broken.