L-Tetrahydropalmatine (L-THP) – Powder, 10g
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L-Tetrahydropalmatine or L-THP is a tetrahydroprotoberberine isoquinoline alkaloid that is known to possess analgesic and anti-inflammatory properties, promotes cardiovascular health, improves mood and reduces stress and anxiety.

Tetrahydropalmatine (THP) is an isoquinoline alkaloid found in several different plant species, mainly in the genus Corydalis (Yan Hu Suo), but also in other plants such as Stephania rotunda. L-Tetrahydropalmatine (L-THP) is the synthetically produced potent enantiomer and has been marketed worldwide as an anxiolytic, sedative, analgesic and relaxant. Preliminary human studies also show its potential in controlling addiction to both cocaine and opiates as it has generated promising results.

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What is L-Tetrahydropalmatine (L-THP)?

L-Tetrahydropalmatine is a berberine alkaloid and a heterotetracyclic compound obtained by the formal addition of two molecules of hydrogen to the pyridine ring of palmatine. It has a role as an adrenergic agent, a non-narcotic analgesic and a dopaminergic antagonist.

L-Tetrahydropalmatine (L-THP) Benefits and Uses

Studies have shown that L-Tetrahydropalmatine  may have the following benefits:

  • Prevents heart disease and liver damage
  • Anti-inflammatory and analgesic properties
  • Improves mood and reduces stress and anxiety

Additional Information on L-Tetrahydropalmatine (L-THP)

Pharmaceutical companies improved the characteristics of Tetrahydropalmatine (THP) by synthesizing it, thus producing the potent enantiomer Levo-THP or L-THP.  The pharmacological profile of L-THP, which includes antagonism of dopamine D1 and D2 receptors and actions at dopamine D3, alpha adrenergic and serotonin receptors suggests that it may have the properties necessary to fight cocaine and opiate addiction.

Where to Buy L-Tetrahydropalmatine (L-THP)?

Botany offers high-quality L-Tetrahydropalmatine powder in a quantity of 10g. Our L-Tetrahydropalmatine has been lab-tested and verified for both product purity and identity.

Suggested Use

For Best Results:

  • Take 30mg orally once a day.
  • Sensitive to flavors? Feel free to mix your powder into your favorite food or drink.
  • Store in a cool, dry place away from light.
  • A 10 gram jar contains 333x 30mg servings.


One Serving (30mg) Contains:

  • L-Tetrahydropalmatine: 30mg
  • Other Ingredients: none
  • No artificial colors, preservatives, or additives.


This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Consult your physician if pregnant, nursing, have or suspect a medical condition.

Do not use if tamper seal is broken.