L-Citrulline – Powder, 100g

L-Citrulline – Powder, 100g



The organic compound citrulline is an α-amino acid. It is a key intermediate in the urea cycle, the pathway by which mammals excrete ammonia by converting it into urea. Citrulline is also produced as a byproduct of the enzymatic production of nitric oxide from the amino acid arginine, catalyzed by nitric oxide synthase.

L-citrulline is the L-enantiomer of citrulline. It has a role as an nitric oxide synthase inhibitor, a protective agent, a nutraceutical, a micronutrient, a human metabolite, an Escherichia coli metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is an enantiomer of a D-citrulline. It is a tautomer of a L-citrulline zwitterion.

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What is L-Citrulline?

Citrulline is a non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. L-citrulline is converted into L-arginine by the enzymes argininosuccinate synthetase and argininosuccinate lyase in the presence of L-aspartate and ATP. Subsequently, L-arginine is converted to nitric oxide by nitric oxide synthase and L-citrulline is regenerated as a by-product.

L-Citrulline Benefits and Uses

Studies have shown that L-Citrulline may have the following benefits:

  • Promotes a healthy heart
  • Supports a robust cardiovascular system
  • Promotes endurance
  • Supports a healthy immune system
  • May support male health and libido

Additional Information on L-Citrulline

L-Citrulline has been shown to support the ammonia recycling process and the metabolism of nitric oxide which may help to support cardiovascular health.

Where to Buy L-Citrulline

Botany offers high-quality L-Citrulline powder in a quantity of 100g. Our L-Citrulline has been lab-tested and verified for both product purity and identity.

Suggested Use

For Best Results:

  • Take 1g orally up to 3 times daily.
  • Sensitive to flavors? Feel free to mix your powder into your favorite food or drink.
  • Store in a cool, dry place away from light.
  • A 100g jar contains 100 x 1g servings.
  • We recommend using a milligram scale to accurately measure dosages.


One Serving (1g) Contains:

  • L-Citrulline 1g
  • Other Ingredients: none.
  • No artificial colors, preservatives, or additives.


This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Consult your physician if pregnant, nursing, have or suspect a medical condition.

Do not use if tamper seal is broken.

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