CBD IsoEx Oil (THC-Free)

CBD IsoEx Oil (THC-Free)

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Pure hemp-derived CBD isolate designed to balance and support the endocannabinoid system.*

Our Pure CBD (THC-Free) oil supplements are made of naturally sourced ingredients. Every ingredient is tested by independent third party laboratories for potency and contaminants including pesticides, residual solvents, toxic heavy metals, microbes and more. We use the highest standard of hemp-derived CBD isolate available and ensure the raw materials are THC-free so you can get all of the benefits without any of the intoxicating effects. Using CBD oil sublingually is a highly effective way to absorb the ingredients so you can get relief faster.

What’s the difference between CBD extracts: CBD isolate (IsoEx), CBD distillate (DistEx), CBD Non-Distilled (NonEx)?

Lab Reports
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Return or exchange your unopened product within 30 days no questions asked. If you are unsatisfied with your product we will issue a full refund. If you need to return a product we will prepay shipping and track the return. Our checkout is SSL encrypted and completely secure. Order today and we will ship the very same day, every business day. Our products are verified by independent third party laboratories to meet quality standards. All product batches and lots are assigned unique identifiers and tied to publicly posted lab reports.


Purified CBD Oil!

Botany’s organic pure CBD isolate oil is the highly-refined essence of hemp contained in one small bottle. It contains pure hemp-derived CBD isolate which is responsible for many of the plant’s therapeutic benefits, without the risk of ingesting THC, which can be intoxicating, and without the hazards of smoking or vaping, which can include consuming harmful byproducts.

Organic Farming Practices

Our organic pure CBD oil is extracted from hand-selected hemp flowers grown solely on pesticide-free family farms in the USA. These flowers are dried, finely ground and extracted. A multi-step process called chromatography follows, removing every trace of plant materials, oils, terpenes, THC and minor cannabinoids to yield a very pure CBDa. The natural CBDa is then gently heated (“decarboxylated”) in an industrial kiln in order to convert it to “the good stuff”: a fully activated, 99%+ pure cannabidiol (CBD) crystalline isolate extract.

Our pure CBD oil is a common favorite and is loved for its clean, high purity and consistent effects!

Pure CBD Benefits

Scientists have discovered abundant evidence to suggest that CBD may support a healthy endocannabinoid system, helping to promote homeostasis in the body.

A few of the widely-reported benefits include:

  • Positive Mood 
  • Relief of Minor Discomforts & Inhibiting Inflammation    
  • Modulating Sleep
  • Promoting a Sense of Calm & Confidence

Positive Mood

A key molecule in the body’s endocannabinoid system is anandamide, a cannabinoid receptor (CB1) agonist named after the Sanskrit word for “bliss.” Anandamide levels can become severely depleted from the lingering effects of PTSD and chronic stress.1,2 In a study of mental health patients, supplementing CBD was found to cause a “significant increase in serum anandamide levels.”3 CBD also activates the 5-HT1A serotonin receptor which can help support positive moods.4

Soothes Minor Discomforts & Inhibits Inflammation

Aspirin, Tylenol, and ibuprofen relieve pain by suppressing COX-2, the enzyme that makes inflammatory chemicals. According to a 2016 study, CBD can also suppress the COX-2 enzyme and it may help reduce inflammation and oxidative stress.9 CBD may also target glycine receptors in the spinal cord.10

Supports Relaxation and Modulates Sleep Relaxation

Relaxation of the mind and body are prerequisites for deep & restful sleep. Cannabinoid receptors are found in the vagus nerve,11 which contains roughly 75% of all the parasympathetic (relaxing) neurons in the body. Adenosine is a natural neuromodulator in our body that helps make us sleepy. If levels of adenosine don’t build up enough during the day it can make us feel ‘wired’ and awake at night. CBD has been shown to boost adenosine levels.12 Some people prefer to take it in the late afternoon or early evening rather than before bed as, in the short term, CBD can promote wakefulness.

Promotes a Sense of Calm & Confidence

A double-blind, randomized clinical trial on 10 humans suggests that CBD may help promote calm social interactions.5 Other studies suggest that supplementing CBD before a public speaking scenario may support feelings of confidence and relaxation. 6,7,8

Product Specifications

Botany infuses pure crystalline CBD powder into organic MCT oil made from coconuts in 1oz (30mL) glass bottles. One full dropper of the clear, tasteless oil is approximately 1mL. We offer several potency options to suit different budgets and relief requirements.

  • Cannabidiol (CBD) infused oil in a liquid dropper bottle for simple dosing.
  • The color of CBD oil can vary from batch to batch. Botany’s products are made without any additives or dyes to standardize the color of our products. That said, what you’re left with is 100% natural CBD oil the way nature intended.
  • Derived from non-GMO, pesticide-free, US-grown commercial hemp.
  • Hemp is grown using natural, organic farming practices.
  • Extracted from aerial plant parts.

Our Commitment to Quality Control & Transparency

Not all CBD is created equal! CBD oil made with inferior extraction and processing techniques can become denatured and less bioactive. It can also get contaminated with toxic chemical solvents & reagents, heavy metals, pesticides, mold, and pathogenic microbes. We won’t personally take anything unless we know it’s pure, nor will our conscience allow us to sell it. That’s why, the moment a new batch arrives at our labeling and distribution facility, the CBD oil is quarantined. It’s set aside until it passes a rigorous panel of safety tests performed by highly respected, third party analytical labs. We provide lab reports for each batch of raw material and every lot of finished products.  That way, you can rest assured that the oil in your bottle is safe and free of contaminants!

100% Customer Satisfaction Guarantee

We understand there are many other companies selling CBD. Botany’s long-term strategy is to compete by offering superior products and customer service. We invite you to try a bottle of our organic pure CBD oil, completely risk-free. If you are not satisfied, simply contact us within 30 days for a prompt and courteous refund.


  1. Transl Psychiatry. 2014 Jul; 4(7): e408.
  2. Neuropsychopharmacology. 2018 Jan;43(1):80-102.
  3. Transl Psychiatry. 2012 Mar; 2(3): e94.
  4. Br J Pharmacol. 2010 Jan;159(1):122-8.
  5. J Psychopharmacol. 2011 Jan;25(1):121-30.
  6. J Psychopharmacol. 1993 Jan;7(1 Suppl):82-8.
  7. Neuropsychopharmacology. 2011 May; 36(6): 1219–1226.
  8. Braz J Psychiatry. 2019 Jan-Feb;41(1):9-14.
  9. Mol Med Rep. 2016 Sep;14(3):2321-7.
  10. J Exp Med. 2012 Jun 4;209(6):1121-34.
  11. Am J Physiol Gastrointest Liver Physiol. 2010 Jul; 299(1): G63–G69.
  12. Proc Natl Acad Sci U S A. 2006 May 16; 103(20): 7895–7900.

Suggested Use

For Best Results:

  • Take 1 mL orally up to three times daily. Adjust dosage as needed.
  • Hold under tongue for 15-30 seconds prior to swallowing.
  • Consistency, as with any CBD supplement, is key for success.
  • Sensitive to flavors? Feel free to mix your oil into your favorite food or drink.
  • Shake well before use. Do not refrigerate. Store in a cool, dry place away from light.
  • A 30mL bottle contains 30x 1mL servings or 60x 0.5mL servings.
  • Dropper use: Gently squeeze the rubber end and release. The dropper will be half full which indicates a “full dropper”. (Oil will not fill the entire dropper)


One Serving (1 mL) Contains:

  • Cannabidiol (CBD) Isolate from Hemp (Aerial Parts) [amount varies with product variant]
  • Other Ingredients: Organic Coconut MCT Oil
  • No artificial colors, preservatives, or additives. Non-GMO. Pesticide-free. Gluten-free. Suitable for vegans.


This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Consult your physician if pregnant, nursing, have or suspect a medical condition.

Do not use if tamper seal is broken.

Reviews (12)


  1. Lifesaver

  2. Great quality! Fast shipping! There was no taste!

  3. I can’t believe how hard it is to find CBD with droppers that allow for accurate dosing. I also love that the dropper is curved which means NO CBD LEFT BEHIND! Worth every penny. Will be buying over and over again.

  4. WOW! I will be a forever customer! Love everything about this!

  5. Tried another brand first did ok, received Botany as a gift and was blown away. What a difference. Well done.


  7. I really dig the oils! I have fallen in love.

  8. Shipping was fast. I’m not some fake review or computer bot. Real guy who lives in California. This is my fourth time buying this product. Best quality I’ve seen.

  9. I’m so grateful to have found a source of such consistently high quality, and reasonably priced clean CBD!

  10. This is wonderful…and the dropper is so well made..the best I’ve seen and I’m a CBD connoisseur.

  11. I was definitely impressed with this tincture. My first experience with CBD was with another brand and it left me skeptical. You guys are on another level.

  12. My functional medicine doctor recommended this product. I let my friend try it and now she won’t give it back! I need another one since she won’t stop calling me to chat about how she benefits from it so much!

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