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Alpha-glycerophosphocholine (Alpha-GPC or α-GPC) is a cholinergic compound that is used for its cognitive-promoting properties, and to enhance power output in athletes. It appears to also support cellular membranes, and may aid in preventing cognitive decline.*
Alpha-GPC rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of acetylcholine. Alpha-GPC is a choline-containing supplement that, although found in a variety of food products that are also rich in choline, appears to be pharmacologically active at higher doses.
Beta Ecdysterone is an endogenous ecdysteroid hormone found in some plants and insects and is believed to have protein stimulating effects which promote increased muscle mass and strength.
Beta Ecdysterone, also known as 20-Hydroxyecdysone (20E) is a naturally occurring ecdysteroid hormone found in some plants and insects which has a similar structure to a compound found in humans associated with muscle growth, strength and recovery. Studies suggest that Beta Ecdysterone may have anabolic-like effects and is believed to have protein stimulating effects promoting increased muscle mass and strength. In arthropods, Beta-Ecdysterone acts through the ecdysone receptor, while in humans it binds to the estrogen receptor beta (ERβ) protein-coding gene.
Curcumin is a biologically active polyphenolic compound found in turmeric that is known to possess properties that may support immune health, relieve pain, aid in digestion, and fights inflammation and oxidation agents.
Curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione), also called diferuloylmethane, is the main natural polyphenol found in the rhizome of Curcuma longa (turmeric). It is the principal curcuminoid of turmeric, a member of the ginger family, Zingiberaceae. Curcumin incorporates several functional groups whose structure was first identified in 1910. The aromatic ring systems, which are phenols, are connected by two α,β-unsaturated carbonyl groups. The diketones form stable enols and are readily deprotonated to form enolates; the α,β-unsaturated carbonyl group is a good Michael acceptor and undergoes nucleophilic addition.
Dihydromyricetin (DHM) is a flavonoid which comes from the purified extract of the Japanese Raisin Tree and is believed to possess antioxidative, anti-inflammatory, anticancer and hepatoprotective properties.
Dihydromyricetin (DHM), also known as Ampelopsin has been used for centuries in preventing intoxication and hangover in Korean and Chinese traditional medicine. DHM works by activating the two enzymes; alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) — which help the body break down and metabolize alcohol faster.
Laxogenin is a member of a group of 40 plant-derived compounds, known as brassinosteroids, which may help support muscle production, enhance physical performance, and support quick recovery.*
Laxogenin, known chemically as 5a-hydroxy laxogenin, is a member of a group of 40 plant-derived compounds, known as brassinosteroids, which have a similar structure to animal steroid hormones. They attach only to the cell surface, which sets off a signal to increase muscle production inside of the cell, and activate a protein, known as AKT1 or protein kinase B, that prevents the breakdown of muscle. Supplementing laxogenin may, therefore, help support muscle production, thermogenesis, enhance physical performance, and support quick recovery from exercise when used in conjunction with a healthy diet and exercise program.
Palmitoylethanolamide or PEA is an endogenous fatty acid amide produced in our body, and in animals and plants and is known to possess neuroprotective, anti-inflammatory, anti-nociceptive (antipain) and anti-convulsant properties.
Palmitoylethanolamide or PEA is an endogenous fatty acid amide, belonging to a class of nuclear factor agonists. PEA inhibits FAAH, the enzyme that breaks down cannabinoids, thus activating peroxisome proliferator activated receptors (PPAR) in cell nuclei of both dorsal root ganglion sensory neurons and glial cells. It has been demonstrated to bind to a receptor in the cell-nucleus and exerts a great variety of biological functions related to chronic pain and inflammation.
Tauroursodeoxycholic acid sodium, more commonly referred to as TUDCA, is a bile salt that may protect against bile acid-induced cell damage and promote healthy liver and digestive function.*
Tauroursodeoxycholic acid sodium, more commonly referred to as TUDCA, is a bile salt that is naturally found in trace amounts in the human body. TUDCA and other water-soluble bile salts like UDCA act as detergents that compete with the toxicity of bile acids and thus indirectly protect cells from damage. Additionally, some studies have shown that TUDCA is able to reduce stress in a cell’s Endoplasmic Reticulum; an organelle in cells that serves as a highway from the nucleus out into the cytoplasm, and aids in folding proteins. Through reducing ER stress, TUDCA has been implicated in a wide range of beneficial metabolic effects such as glucose metabolism and protecting neurons.
TUDCA Acid is an orally bioavailable and effective inhibitor of apoptosis by exhibiting antioxidant properties, maintaining mitochondrial membrane potential, and preventing cytochrome c release.
Tauroursodeoxycholic acid, more commonly referred to as TUDCA, is a bile salt that is found naturally occurring in the body. When regular bile salts reach the intestines, they can be metabolized by bacteria into UDCA and then later bound to a taurine molecule to become TUDCA. TUDCA is able to reduce stress to any cell’s Endoplasmic Reticulum; an organelle in cells that serves as a highway from the nucleus out into the cytoplasm, and aids in folding proteins. Through reducing ER stress, TUDCA has been implicated in a wide range of beneficial metabolic effects such as reducing insulin resistance and diabetes, being a neurological protection agent and has been used for conditions called liver cholestasis.